Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells

The stability of a lineage program (cellular memory) is dependent on mechanisms that epigenetically maintain active or repressed states of gene expression (transcriptional memory). Although epigenetic silencing of genes has been clearly demonstrated from yeast to mammals, heritable maintenance of ac...

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Main Authors: Chong, Mark M.W., Simpson, Natalie, Ciofani, Maria, Chen, Grace, Collins, Amélie, Littman, Dan R.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849123/
https://ncbi.nlm.nih.gov/pubmed/20360383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1901610
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