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Role of EGFR degradation in cisplatin-induced cytotoxicity in head and neck cancer

Cisplatin and its analogues are the most commonly used agents in the treatment of head and neck squamous cell carcinoma (HNSCC). In this study, we investigated a possible role of epidermal growth factor receptor (EGFR), phosphorylation and degradation in cisplatin-induced cytotoxicity. Cisplatin tre...

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Detalhes bibliográficos
Main Authors: Ahsan, A, Hiniker, SM, Ramanand, SG, Nyati, S, Hegde, A, Helman, A, Menawat, R, Bhojani, MS, Lawrence, TS, Nyati, MK
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848889/
https://ncbi.nlm.nih.gov/pubmed/20215522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4294
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