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Inhibition of Pyk2 Blocks Airway Inflammation and Hyperresponsiveness in a Mouse Model of Asthma

The objective of this investigation was to determine the role of Pyk2, an intracellular nonreceptor protein tyrosine kinase for postadhesive inflammatory cell migration, on airway inflammation and hyperresponsiveness in immune-sensitized mice. Blockade of Pyk2 was effected by intraperitoneal adminis...

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書誌詳細
主要な著者: Duan, Yingli, Learoyd, Jonathan, Meliton, Angelo Y., Clay, Bryan S., Leff, Alan R., Zhu, Xiangdong
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848740/
https://ncbi.nlm.nih.gov/pubmed/19520918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0469OC
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