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THEMIS, a new T cell specific protein important for late thymocyte development

During positive selection, thymocytes transition through a stage during which T cell receptor (TCR) signaling controls CD4 versus CD8 lineage choice and subsequent maturation. Here, we describe a new T cell specific protein, THEMIS, that performs a distinct function during this stage. In Themis(-/-)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lesourne, Renaud, Uehara, Shoji, Lee, Jan, Song, Ki-Duk, Li, LiQi, Pinkhasov, Julia, Zhang, Yongqing, Weng, Nan-Ping, Wildt, Kathryn F., Wang, Lie, Bosselut, Remy, Love, Paul E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848698/
https://ncbi.nlm.nih.gov/pubmed/19597498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1768
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