CXCR4 Mediated Chemotaxis Is Regulated by 5T4 Oncofetal Glycoprotein in Mouse Embryonic Cells

5T4 oncofetal molecules are highly expressed during development and upregulated in cancer while showing only low levels in some adult tissues. Upregulation of 5T4 expression is a marker of loss of pluripotency in the early differentiation of embryonic stem (ES) cells and forms an integrated componen...

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Detalhes bibliográficos
Main Authors: Southgate, Thomas D., McGinn, Owen J., Castro, Fernanda V., Rutkowski, Andrzej J., Al-Muftah, Mariam, Marinov, Georgi, Smethurst, Graeme J., Shaw, David, Ward, Christopher M., Miller, Crispin J., Stern, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848608/
https://ncbi.nlm.nih.gov/pubmed/20376365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009982
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