Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia

Por McGinn, Owen J., Krishnan, Shekhar, Bourquin, Jean-Pierre, Sapra, Puja, Dempsey, Clare, Saha, Vaskar, Stern, Peter L.
Publicado no Haematologica (2017)

5T4 oncofoetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype

Por Castro, Fernanda V, McGinn, Owen J, Krishnan, Shekhar, Marinov, Georgi, Li, Jian, Rutkowski, Andrzej J, Elkord, Eyad, Burt, Debbie, Holland, Mark, Vaghjiani, Rasilaben, Gallego, Aurelia, Saha, Vaskar, Stern, Peter L
Publicado em 2012

CXCR4 Mediated Chemotaxis Is Regulated by 5T4 Oncofetal Glycoprotein in Mouse Embryonic Cells

Por Southgate, Thomas D., McGinn, Owen J., Castro, Fernanda V., Rutkowski, Andrzej J., Al-Muftah, Mariam, Marinov, Georgi, Smethurst, Graeme J., Shaw, David, Ward, Christopher M., Miller, Crispin J., Stern, Peter L.
Publicado em 2010