5T4 oncofoetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype

Although the overall prognosis in childhood acute lymphoblastic leukaemia (ALL) is good, outcome after relapse is poor. Recurrence is frequently characterised by the occurrence of disease at extramedullary sites such as the central nervous system and testes. Subpopulations of blasts able to migrate...

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Main Authors: Castro, Fernanda V, McGinn, Owen J, Krishnan, Shekhar, Marinov, Georgi, Li, Jian, Rutkowski, Andrzej J, Elkord, Eyad, Burt, Debbie, Holland, Mark, Vaghjiani, Rasilaben, Gallego, Aurelia, Saha, Vaskar, Stern, Peter L
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378689/
https://ncbi.nlm.nih.gov/pubmed/22266911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.18
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