Disheveled Hair and Ear (Dhe), a Spontaneous Mouse Lmna Mutation Modeling Human Laminopathies

BACKGROUND: Investigations of naturally-occurring mutations in animal models provide important insights and valuable disease models. Lamins A and C, along with lamin B, are type V intermediate filament proteins which constitute the proteinaceous boundary of the nucleus. LMNA mutations in humans caus...

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Detalhes bibliográficos
Main Authors: Odgren, Paul R., Pratt, Craig H., MacKay, Carole A., Mason-Savas, April, Curtain, Michelle, Shopland, Lindsay, Ichicki, Tsutomu, Sundberg, John P., Donahue, Leah Rae
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848607/
https://ncbi.nlm.nih.gov/pubmed/20376364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009959
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