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A truncated lamin A in the Lmna(−/−) mouse line: Implications for the understanding of laminopathies

During recent years a number of severe clinical syndromes, collectively termed laminopathies, turned out to be caused by various, distinct mutations in the human LMNA gene. Arising from this, remarkable progress has been made to unravel the molecular pathophysiology underlying these disorders. A gre...

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Detalhes bibliográficos
Main Authors: Jahn, Daniel, Schramm, Sabine, Schnölzer, Martina, Heilmann, Clemens J., de Koster, Chris G., Schütz, Wolfgang, Benavente, Ricardo, Alsheimer, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474667/
https://ncbi.nlm.nih.gov/pubmed/22895093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.21676
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