A truncated lamin A in the Lmna(−/−) mouse line: Implications for the understanding of laminopathies

During recent years a number of severe clinical syndromes, collectively termed laminopathies, turned out to be caused by various, distinct mutations in the human LMNA gene. Arising from this, remarkable progress has been made to unravel the molecular pathophysiology underlying these disorders. A gre...

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Bibliografiske detaljer
Main Authors: Jahn, Daniel, Schramm, Sabine, Schnölzer, Martina, Heilmann, Clemens J., de Koster, Chris G., Schütz, Wolfgang, Benavente, Ricardo, Alsheimer, Manfred
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474667/
https://ncbi.nlm.nih.gov/pubmed/22895093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.21676
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