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Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers

AIMS: To characterize the effects of levofloxacin on QT interval in healthy subjects and the most appropriate oral positive control treatments for International Conference on Harmonization (ICH) E14 QT/QTc studies. METHODS: Healthy subjects received a single dose of levofloxacin (1000 or 1500 mg), m...

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Detaylı Bibliyografya
Asıl Yazarlar: Taubel, Jorg, Naseem, Asif, Harada, Tomohiko, Wang, Duolao, Arezina, Radivoj, Lorch, Ulrike, Camm, A John
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848412/
https://ncbi.nlm.nih.gov/pubmed/20406223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03595.x
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