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Insulin regulates alveolar epithelial function by inducing Na(+)/K(+)-ATPase translocation to the plasma membrane in a process mediated by the action of Akt

Stimulation of Na(+)/K(+)-ATPase translocation to the cell surface increases active Na(+) transport, which is the driving force of alveolar fluid reabsorption, a process necessary to keep the lungs free of edema and to allow normal gas exchange. Here, we provide evidence that insulin increases alveo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Comellas, Alejandro P., Kelly, Aileen M., Trejo, Humberto E., Briva, Arturo, Lee, Joyce, Sznajder, Jacob I., Dada, Laura A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848117/
https://ncbi.nlm.nih.gov/pubmed/20332111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.066464
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