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Endothelin-1 Impairs Alveolar Epithelial Function via Endothelial ET(B) Receptor

Rationale: Endothelin-1 (ET-1) is increased in patients with high-altitude pulmonary edema and acute respiratory distress syndrome, and these patients have decreased alveolar fluid reabsorption (AFR). Objectives: To determine whether ET-1 impairs AFR via activation of endothelial cells and nitric ox...

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Main Authors: Comellas, Alejandro P., Briva, Arturo, Dada, Laura A., Butti, Maria L., Trejo, Humberto E., Yshii, Cecilia, Azzam, Zaher S., Litvan, Juan, Chen, Jiwang, Lecuona, Emilia, Pesce, Liuska M., Yanagisawa, Masashi, Sznajder, Jacob I.
格式: Artigo
語言:Inglês
出版: American Thoracic Society 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633058/
https://ncbi.nlm.nih.gov/pubmed/18948426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200804-540OC
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