Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report

INTRODUCTION: Dexmedetomidine is a selective and potent alpha2-adrenoceptor agonist licensed for use in the sedation of patients initially ventilated in intensive care units at a maximum dose rate of 0.7 μg/kg/h administered for up to 24 hours. Higher dose rates and longer infusion periods are somet...

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Main Authors: Iirola, Timo, Laitio, Ruut, Kentala, Erkki, Aantaa, Riku, Kurvinen, Juha-Pekka, Scheinin, Mika, Olkkola, Klaus T
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Case report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848065/
https://ncbi.nlm.nih.gov/pubmed/20184754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-1947-4-73
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