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Population Modelling of Dexmedetomidine Pharmacokinetics and Haemodynamic Effects After Intravenous and Subcutaneous Administration
BACKGROUND AND OBJECTIVE: Dexmedetomidine is a potent agonist of α(2)-adrenoceptors causing dose-dependent sedation in humans. Intravenous dexmedetomidine is commonly used perioperatively, but an extravascular route of administration would be favoured in palliative care. Subcutaneous infusions provi...
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| Veröffentlicht in: | Clin Pharmacokinet |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7658092/ https://ncbi.nlm.nih.gov/pubmed/32462542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-020-00900-3 |
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