Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients

INTRODUCTION: Only limited information exists on the pharmacokinetics of prolonged (> 24 hours) and high-dose dexmedetomidine infusions in critically ill patients. The aim of this study was to characterize the pharmacokinetics of long dexmedetomidine infusions and to assess the dose linearity of...

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Detalhes bibliográficos
Main Authors: Iirola, Timo, Aantaa, Riku, Laitio, Ruut, Kentala, Erkki, Lahtinen, Maria, Wighton, Andrew, Garratt, Chris, Ahtola-Sätilä, Tuula, Olkkola, Klaus T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334808/
https://ncbi.nlm.nih.gov/pubmed/22030215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10518
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