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On the paternal origin of trisomy 21 Down syndrome

BACKGROUND: Down syndrome (DS), characterized by an extra free chromosome 21 is the most common genetic cause for congenital malformations and learning disability. It is well known that the extra chromosome 21 originates from the mother in more than 90% of cases, the incidence increases with materna...

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Bibliografische gegevens
Hoofdauteurs: Hultén, Maj A, Patel, Suketu D, Westgren, Magnus, Papadogiannakis, Nikos, Jonsson, Anna Maria, Jonasson, Jon, Iwarsson, Erik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848052/
https://ncbi.nlm.nih.gov/pubmed/20178584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-3-4
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