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Maternal Germinal Trisomy 21 in Down Syndrome

It has now been over 50 years since it was discovered that Down syndrome is caused by an extra chromosome 21, i.e., trisomy 21. In the interim, it has become clear that in the majority of cases, the extra chromosome is inherited from the mother, and there is, in this respect, a strong maternal age e...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Hultén, Maj A., Öijerstedt, Linn, Iwarsson, Erik, Jonasson, Jon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449669/
https://ncbi.nlm.nih.gov/pubmed/26237255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm3010167
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