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Maternal Germinal Trisomy 21 in Down Syndrome

It has now been over 50 years since it was discovered that Down syndrome is caused by an extra chromosome 21, i.e., trisomy 21. In the interim, it has become clear that in the majority of cases, the extra chromosome is inherited from the mother, and there is, in this respect, a strong maternal age e...

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Détails bibliographiques
Publié dans:J Clin Med
Auteurs principaux: Hultén, Maj A., Öijerstedt, Linn, Iwarsson, Erik, Jonasson, Jon
Format: Artigo
Langue:Inglês
Publié: MDPI 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449669/
https://ncbi.nlm.nih.gov/pubmed/26237255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm3010167
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