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On the origin of trisomy 21 Down syndrome

BACKGROUND: Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability. It is well known that the extra chromosome 21 most often originates from the mother, the incidence increases with maternal age, there may be aberr...

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Bibliografische gegevens
Hoofdauteurs: Hultén, Maj A, Patel, Suketu D, Tankimanova, Maira, Westgren, Magnus, Papadogiannakis, Nikos, Jonsson, Anna Maria, Iwarsson, Erik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564957/
https://ncbi.nlm.nih.gov/pubmed/18801168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-1-21
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