Stoichiometry and intracellular fate of TRIM-containing TCR complexes

BACKGROUND: Studying the stoichiometry and intracellular trafficking of the T cell antigen receptor (TCR) is pivotal in understanding its mechanisms of activation. The αβTCR includes the antigen-binding TCRαβ heterodimer as well as the signal transducing CD3εγ, CD3εδ and ζ(2 )subunits. Although the...

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Hauptverfasser: Swamy, Mahima, Siegers, Gabrielle M, Fiala, Gina J, Molnar, Eszter, Dopfer, Elaine P, Fisch, Paul, Schraven, Burkhart, Schamel, Wolfgang WA
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848047/
https://ncbi.nlm.nih.gov/pubmed/20298603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-8-5
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