The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain

T cell receptor (TCR)-interacting molecule (TRIM) is a recently identified transmembrane adaptor protein, which is exclusively expressed in T cells. Here we demonstrate that in mature T cells, TRIM preferentially interacts with the TCR via the TCR-ζ chains and to a lesser extent via the CD3-ε/γ hete...

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Main Authors: Kirchgessner, Henning, Dietrich, Jes, Scherer, Jeanette, Isomäki, Pia, Korinek, Vladimir, Hilgert, Ivan, Bruyns, Eddy, Leo, Albrecht, Cope, Andrew P., Schraven, Burkhart
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193385/
https://ncbi.nlm.nih.gov/pubmed/11390434
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