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T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity
The T-cell antigen receptor (TCR•CD3) is a multi-subunit complex that is responsible for triggering an adaptive immune response. It shows high specificity and sensitivity, while having a low affinity for the ligand. Furthermore, T cells respond to antigen over a wide concentration range. The stoichi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479560/ https://ncbi.nlm.nih.gov/pubmed/16670682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400682 |
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