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T-cell antigen-receptor stoichiometry: pre-clustering for sensitivity

The T-cell antigen receptor (TCR•CD3) is a multi-subunit complex that is responsible for triggering an adaptive immune response. It shows high specificity and sensitivity, while having a low affinity for the ligand. Furthermore, T cells respond to antigen over a wide concentration range. The stoichi...

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Sonraí Bibleagrafaíochta
Main Authors: Alarcón, Balbino, Swamy, Mahima, van Santen, Hisse M, Schamel, Wolfgang W A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479560/
https://ncbi.nlm.nih.gov/pubmed/16670682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400682
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