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Mechanisms by which Human DNA Primase Chooses to Polymerize a NTP

Human DNA primase synthesizes short RNA primers that DNA polymerase α then elongates during the initiation of all new DNA strands. Even though primase misincorporates NTPs at a relatively high frequency, this likely does not impact the final DNA product since the RNA primer is replaced with DNA. We...

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Bibliografische gegevens
Hoofdauteurs: Urban, Milan, Joubert, Nicolas, Hocek, Michal, Kuchta, Robert D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847881/
https://ncbi.nlm.nih.gov/pubmed/20030400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9019516
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