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Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate Yet Selective Polymerase
Herpes simplex virus-1 primase misincorporates the natural NTPs at frequencies around 1 error per 30 NTPs polymerized, making it one of the least accurate polymerases known. We used a series of nucleotide analogues to further test the hypothesis that primase requires Watson-Crick hydrogen bond forma...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2784104/ https://ncbi.nlm.nih.gov/pubmed/19835416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901476k |
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