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Toll-like receptor-mediated dendritic cell-dependent and -independent stimulation of innate and adaptive immunity

Toll-like receptors (TLRs) play prominent roles in initiating adaptive immune responses to infection, but their roles in particular cell types in vivo are not established. Here we report the generation of mice selectively lacking the crucial TLR-signaling adaptor MyD88 in dendritic cells (DCs). In t...

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Hlavní autoři: Hou, Baidong, Reizis, Boris, DeFranco, Anthony L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847796/
https://ncbi.nlm.nih.gov/pubmed/18656388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.05.016
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