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Toll-like receptor-mediated dendritic cell-dependent and -independent stimulation of innate and adaptive immunity
Toll-like receptors (TLRs) play prominent roles in initiating adaptive immune responses to infection, but their roles in particular cell types in vivo are not established. Here we report the generation of mice selectively lacking the crucial TLR-signaling adaptor MyD88 in dendritic cells (DCs). In t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847796/ https://ncbi.nlm.nih.gov/pubmed/18656388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.05.016 |
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