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Critical coordination of innate immune defense against Toxoplasma gondii by dendritic cells responding via their Toll-like receptors

Toll-like receptors (TLRs) play an important role in host defense against a variety of microbial pathogens. We addressed the mechanism by which TLRs contribute to host defense against the lethal parasite Toxoplasma gondii by using mice with targeted inactivation of the TLR adaptor protein myeloid di...

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Библиографические подробности
Главные авторы: Hou, Baidong, Benson, Alicia, Kuzmich, Lili, DeFranco, Anthony L., Yarovinsky, Felix
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017180/
https://ncbi.nlm.nih.gov/pubmed/21173242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011549108
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