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Innate Immune Response to Adenoviral Vectors Is Mediated by both Toll-Like Receptor-Dependent and -Independent Pathways

Recombinant adenoviral vectors have been widely used for gene therapy applications and as vaccine vehicles for treating infectious diseases such as human immunodeficiency virus disease. The innate immune response to adenoviruses represents the most significant hurdle in clinical application of adeno...

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Bibliografiske detaljer
Main Authors: Zhu, Jiangao, Huang, Xiaopei, Yang, Yiping
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866082/
https://ncbi.nlm.nih.gov/pubmed/17229689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02192-06
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