Genome-wide analysis of histone modifications in human pancreatic islets

The global diabetes epidemic poses a major challenge. Epigenetic events contribute to the etiology of diabetes; however, the lack of epigenomic analysis has limited the elucidation of the mechanistic basis for this link. To determine the epigenetic architecture of human pancreatic islets we mapped t...

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Detalhes bibliográficos
Main Authors: Bhandare, Reena, Schug, Jonathan, Le Lay, John, Fox, Alan, Smirnova, Olga, Liu, Chengyang, Naji, Ali, Kaestner, Klaus H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847745/
https://ncbi.nlm.nih.gov/pubmed/20181961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.102038.109
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