Nalaganje...
Atomistic Simulations of the Effects of Polyglutamine Chain Length and Solvent Quality on Conformational Equilibria and Spontaneous Homodimerization
Aggregation of expanded polyglutamine tracts is associated with nine different neurodegenerative diseases, including Huntington’s disease. Experiments and computer simulations have demonstrated that monomeric forms of polyglutamine molecules sample heterogeneous sets of collapsed structures in water...
Shranjeno v:
| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847503/ https://ncbi.nlm.nih.gov/pubmed/18824003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.09.026 |
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