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Effective Depletion of Regulatory T Cells Allows the Recruitment of Mesothelin‐Specific CD8(+) T Cells to the Antitumor Immune Response Against a Mesothelin‐Expressing Mouse Pancreatic Adenocarcinoma
Vaccine‐induced CD8(+) T‐cell responses can eradicate developing tumors in vivo in mouse models. Translating these successes into approved treatments for cancer patients has been challenging, since many of these models lack expression of clinically proven/relevant tumor antigens. We have shown that...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Inc
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847413/ https://ncbi.nlm.nih.gov/pubmed/20357913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00070.x |
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