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Developmental and oncogenic effects of Insulin-like Growth Factor-I in Ptc1(+/- )mouse cerebellum
BACKGROUND: Medulloblastoma is amongst the most common malignant brain tumors in childhood, arising from neoplastic transformation of granule neuron precursors (GNPs) of the cerebellum via deregulation of pathways involved in cerebellar development. Deregulation of the Sonic hedgehog/Patched1 (Shh/P...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2846887/ https://ncbi.nlm.nih.gov/pubmed/20214787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-53 |
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