Effect of Allopurinol versus Urate Oxidase on Methotrexate Pharmacokinetics in Children with Newly Diagnosed Acute Lymphoblastic Leukemia

BACKGROUND: Allopurinol and urate oxidase are both effective in preventing or treating hyperuricemia during remission induction therapy for lymphoid malignancies, but their effect on concomitant anticancer drug therapy has not been compared. METHODS: We compared plasma methotrexate pharmacokinetics...

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Detaylı Bibliyografya
Asıl Yazarlar: Crews, Kristine R., Zhou, Yinmei, Pauley, Jennifer L., Howard, Scott C., Jeha, Sima, Relling, Mary V., Pui, Ching-Hon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846832/
https://ncbi.nlm.nih.gov/pubmed/19834958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24681
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