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Kinetic and Chemical Mechanism of Arylamine N-Acetyltransferase from Mycobacterium tuberculosis

Arylamine N-acetyltransferases (NATs) are cytosolic enzymes that catalyze the transfer of the acetyl group from acetyl coenzyme A (AcCoA) to the free amino group of arylamines and hydrazines. Previous studies have reported that overexpression of NAT from Mycobacterium smegmatis and Mycobacterium tub...

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Detalhes bibliográficos
Main Authors: Sikora, Alison L., Frankel, Brenda A., Blanchard, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846785/
https://ncbi.nlm.nih.gov/pubmed/18795795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800398c
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