Mechanism of inhibition of DNA gyrase by cyclothialidine, a novel DNA gyrase inhibitor.
We investigated how cyclothialidine (Ro 09-1437), a novel DNA gyrase inhibitor belonging to a new chemical class of compounds, acts to inhibit Escherichia coli DNA gyrase. Cyclothialidine up to 100 micrograms/ml showed no effect on DNA gyrase when linear DNA was used as a substrate. Under the same c...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284669/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7811004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.9.1966 |
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