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Differential sensitivity of gene expression in vitro to inhibitors of DNA gyrase.

We have used the antibiotics coumermycin A1, novobiocin, and oxolinic acid, which are specific inhibitors of DNA gyrase, to study the coupled transcription and translation of several bacterial and plasmid genes in a DNA-directed cell-free system. The expression of different genes is reduced to diffe...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yang, H L, Heller, K, Gellert, M, Zubay, G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1979
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383813/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/226966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.7.3304
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