Differential sensitivity of gene expression in vitro to inhibitors of DNA gyrase.

We have used the antibiotics coumermycin A1, novobiocin, and oxolinic acid, which are specific inhibitors of DNA gyrase, to study the coupled transcription and translation of several bacterial and plasmid genes in a DNA-directed cell-free system. The expression of different genes is reduced to diffe...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Yang, H L, Heller, K, Gellert, M, Zubay, G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1979
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383813/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/226966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.7.3304
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