Isoform-Specific Regulation and Localization of the Coxsackie and Adenovirus Receptor in Human Airway Epithelia

Adenovirus is an important respiratory pathogen. Adenovirus fiber from most serotypes co-opts the Coxsackie-Adenovirus Receptor (CAR) to bind and enter cells. However, CAR is a cell adhesion molecule localized on the basolateral membrane of polarized epithelia. Separation from the lumen of the airwa...

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Main Authors: Excoffon, Katherine J. D. A., Gansemer, Nicholas D., Mobily, Matthew E., Karp, Philip H., Parekh, Kalpaj R., Zabner, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845650/
https://ncbi.nlm.nih.gov/pubmed/20361046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009909
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