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Pancratistatin induces apoptosis in clinical leukemia samples with minimal effect on non-cancerous peripheral blood mononuclear cells

BACKGROUND: Pancratistatin, a natural compound extracted from Hymenocallis littoralis, can selectively induce apoptosis in several cancer cell lines. In this ex vivo study, we evaluated the effect of pancratistatin on peripheral blood mononuclear cells obtained from 15 leukemia patients prior to cli...

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Detalhes bibliográficos
Main Authors: Griffin, Carly, Hamm, Caroline, McNulty, James, Pandey, Siyaram
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845577/
https://ncbi.nlm.nih.gov/pubmed/20205924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-6
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