Selective cytotoxicity of Pancratistatin-related natural Amaryllidaceae alkaloids: evaluation of the activity of two new compounds

BACKGROUND: Pancratistatin (PST), a compound extracted from an Amaryllidaceae (AMD) family plant, has been shown to specifically induce apoptosis in cancer cells with no/minimal toxic effect on normal cells. A systematic synthetic approach has indicated that the minimum cytotoxic pharmacophore compr...

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Bibliografiset tiedot
Päätekijät: Griffin, Carly, Sharda, Natasha, Sood, Divya, Nair, Jerald, McNulty, James, Pandey, Siyaram
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2007
Aiheet:
Primary Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892540/
https://ncbi.nlm.nih.gov/pubmed/17550595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-7-10
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