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A novel human heparanase splice variant, T5, endowed with protumorigenic characteristics

Heparanase is a mammalian endo-β-d-glucuronidase that can cleave heparan sulfate side chains, an activity strongly implicated in tumor cell dissemination. The current study aimed to identify and characterize heparanase splice variants. LEADS, Compugen’s alternative splicing modeling platform (Compug...

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Bibliografske podrobnosti
Main Authors: Barash, Uri, Cohen-Kaplan, Victoria, Arvatz, Gil, Gingis-Velitski, Svetlana, Levy-Adam, Flonia, Nativ, Ofer, Shemesh, Ronen, Ayalon-Sofer, Michal, Ilan, Neta, Vlodavsky, Israel
Format: Artigo
Jezik:Inglês
Izdano: The Federation of American Societies for Experimental Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845434/
https://ncbi.nlm.nih.gov/pubmed/20007507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-147074
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