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Tumorigenic and adhesive properties of heparanase
Heparanase is an endo-β-glucuronidase that cleaves heparan sulfate side chains presumably at sites of low sulfation, activity that is strongly implicated with cell invasion associated with cancer metastasis, a consequence of structural modification that loosens the extracellular matrix barrier. In a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941534/ https://ncbi.nlm.nih.gov/pubmed/20619346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.06.005 |
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