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Heparanase induces Akt phosphorylation via a lipid raft receptor
The endoglycosidase heparanase is the predominant enzyme that degrades heparan sulfate side chains of heparan sulfate proteoglycans, activity that is strongly implicated in tumor metastasis. Apart of its well characterized enzymatic activity, heparanase was noted to exert also enzymatic-independent...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390716/ https://ncbi.nlm.nih.gov/pubmed/17689495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.06.188 |
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