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Low and high affinity receptors mediate cellular uptake of heparanase

Heparanase is an endoglycosidase which cleaves heparan sulfate and hence participates in degradation and remodeling of the extracellular matrix. Importantly, heparanase activity correlated with the metastatic potential of tumor-derived cells, attributed to enhanced cell dissemination as a consequenc...

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Detalhes bibliográficos
Main Authors: Ben-Zaken, Olga, Shafat, Itay, Gingis-Velitski, Svetlana, Bangio, Haim, Kelson, Idil Kasuto, Alergand, Tal, Amor, Yehudit, Maya, Ruth Ben-Yakar, Vlodavsky, Israel, Ilan, Neta
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2358949/
https://ncbi.nlm.nih.gov/pubmed/17981072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2007.09.003
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