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Low and high affinity receptors mediate cellular uptake of heparanase
Heparanase is an endoglycosidase which cleaves heparan sulfate and hence participates in degradation and remodeling of the extracellular matrix. Importantly, heparanase activity correlated with the metastatic potential of tumor-derived cells, attributed to enhanced cell dissemination as a consequenc...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2358949/ https://ncbi.nlm.nih.gov/pubmed/17981072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2007.09.003 |
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