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Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination

Bloom’s syndrome (BS) is an autosomal recessive disorder characterized by growth retardation, cancer predisposition, and sterility. BS mutated (Blm), the gene mutated in BS patients, is one of five mammalian RecQ helicases. Although BLM has been shown to promote genome stability by assisting in the...

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Detalles Bibliográficos
Main Authors: Holloway, J. Kim, Morelli, Meisha A., Borst, Peter L., Cohen, Paula E.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845075/
https://ncbi.nlm.nih.gov/pubmed/20308424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909048
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