Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites

Meiotic crossovers (COs) are crucial for ensuring accurate homologous chromosome segregation during meiosis I. Because the double-strand breaks (DSBs) that initiate meiotic recombination greatly outnumber eventual COs, this process requires exquisite regulation to narrow down the pool of DSB interme...

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Autores principales: Holloway, J. Kim, Sun, Xianfei, Yokoo, Rayka, Villeneuve, Anne M., Cohen, Paula E.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050721/
https://ncbi.nlm.nih.gov/pubmed/24891606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201401122
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