Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites

Meiotic crossovers (COs) are crucial for ensuring accurate homologous chromosome segregation during meiosis I. Because the double-strand breaks (DSBs) that initiate meiotic recombination greatly outnumber eventual COs, this process requires exquisite regulation to narrow down the pool of DSB interme...

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Bibliografiska uppgifter
Huvudupphovsmän: Holloway, J. Kim, Sun, Xianfei, Yokoo, Rayka, Villeneuve, Anne M., Cohen, Paula E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2014
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050721/
https://ncbi.nlm.nih.gov/pubmed/24891606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201401122
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