Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites

Meiotic crossovers (COs) are crucial for ensuring accurate homologous chromosome segregation during meiosis I. Because the double-strand breaks (DSBs) that initiate meiotic recombination greatly outnumber eventual COs, this process requires exquisite regulation to narrow down the pool of DSB interme...

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Bibliographic Details
Main Authors: Holloway, J. Kim, Sun, Xianfei, Yokoo, Rayka, Villeneuve, Anne M., Cohen, Paula E.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050721/
https://ncbi.nlm.nih.gov/pubmed/24891606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201401122
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