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Mammalian BLM helicase is critical for integrating multiple pathways of meiotic recombination

Bloom’s syndrome (BS) is an autosomal recessive disorder characterized by growth retardation, cancer predisposition, and sterility. BS mutated (Blm), the gene mutated in BS patients, is one of five mammalian RecQ helicases. Although BLM has been shown to promote genome stability by assisting in the...

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Bibliografiske detaljer
Main Authors: Holloway, J. Kim, Morelli, Meisha A., Borst, Peter L., Cohen, Paula E.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845075/
https://ncbi.nlm.nih.gov/pubmed/20308424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200909048
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