載入...

The H-loop in the Second Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator is Required for Efficient Chloride Channel Closing

The cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-binding cassette (ABC) transporter that functions as a cAMP-activated chloride channel. The recent model of CFTR gating predicts that the ATP binding to both nucleotide-binding domains (NBD1 and NBD2) of CFTR is required for th...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Kloch, Monika, Milewski, Michał, Nurowska, Ewa, Dworakowska, Beata, Cutting, Garry R., Dołowy, Krzysztof
格式: Artigo
語言:Inglês
出版: S. Karger AG 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844707/
https://ncbi.nlm.nih.gov/pubmed/20110677
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!